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WebJan 3, 2024 · Chemotherapeutic drugs are used to treat advanced stages of cancer or following surgery. However, cancers often develop resistance against drugs, leading to failure of treatment and recurrence of the disease. Polyphenols are a family of organic compounds with more than 10,000 members which have a three-membered flavan ring … WebDec 7, 2024 · Mechanism of Drug Resistance. The mechanism of drug resistance at tumor tissue level is extremely complicated. Commonly, tumor heterogeneity, tumor microenvironment (TME), drug transporter and multidrug resistance, cancer stem cells (CSCs), epithelial-mesenchymal transition (EMT) and tumor metastasis are known as the … WebJan 20, 2024 · Introduction. Laryngeal squamous cell carcinoma (LSCC) is one of the most common subtypes of laryngeal cancers and has the second highest incidence among respiratory tumors 1.Notably, the occurrence of LSCC in China is approximately four times higher than that in the United States, with >15,000 estimated deaths each year 2.For … shop amber lewis interiors