Web4 mar. 2024 · Retinal ischemia / reperfusion (IR) injury involves many ophthalmic diseases, such as diabetic retinopathy, ocular ischemic syndrome, glaucoma and ischemic optic neuropathy, which can lead to irreversible neuronal cell damage. 1, 2Studies speculate that oxidative stress may be related to IR-induced retinal damage. 3, 4 Oxidative stress … Web26 mar. 2024 · The mechanistic target of rapamycin (mTOR) is a key mediator of energy metabolism, cell growth, and survival. While previous studies using transgenic mice with …
mTOR activation protects liver from …
Web1 iun. 2015 · Intraperitoneal injection of dexmedetomidine significantly protected intestine IR injury in rats by inhibiting the inflammatory response, intestinal epithelial apoptosis, and maintaining structural integrity of intestinal cells. Objective(s): Intestinal ischemia-reperfusion is a major problem, which may lead to multiorgan failure and death. The aim … WebWe investigated the role of mammalian target of rapamycin/nuclear factor-kappa B (mTOR/NF-κB) signaling pathway in high thoracic epidural anesthesia (HTEA) against … healthy kids dental providers michigan
Cardiac mTOR protects the heart against ischemia-reperfusion injury ...
Web5 mar. 2024 · The cerebral ischemia injury can result in neuronal death and/or functional impairment, which leads to further damage and dysfunction after recovery of blood supply. Cerebral ischemia/reperfusion injury (CIRI) often causes irreversible brain damage and neuronal injury and death, which involves many complex pathological processes … WebThe mechanistic target of rapamycin (mTOR) is a key mediator of energy metabolism, cell growth, and survival. While previous studies using transgenic mice with cardiac-specific overexpression of mTOR (mTOR-Tg) demonstrated the protective effects of cardiac mTOR against ischemia–reperfusion (I/R) injury in both ex vivo and in vivo models, the … Web4 mar. 2024 · TSC2-SA hearts exhibited increased mTOR activation upon reperfusion but not during IPC, indicating that IPC per se may augment mTOR signaling during … moto thai yoga